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1.Yongbin Tong#, Qi Zhang#, Yutong Chen, Zhiqiang Zhao, Jingqi Li, Jinyi Wang, Haishan Xia, Danyi Lu*, Yuyu Liu*. The nuclear receptor REV-ERB¦Á regulates coumarin hepatotoxicity via DBP-dependent repression of CYP2A5 in mice. Expert Opinion on Drug Metabolism & Toxicology. 2025. In press.
2.Dihao Xie, Simin Zhong, Meixue Luo, Jiahao Xu, Ruoyan Zheng, Jiading Luo, Yiting Wang, Yongxing Guo, Lianxia Guo, Baojian Wu*, Danyi Lu*. Disruption of local circadian clocks in aristolochic acid-induced nephropathy in mice. Phytomedicine. 2024.135:156235.
3.Caimei Wu#, Meixue Luo#, Dihao Xie, Simin Zhong, Jiahao Xu, Danyi Lu*. Kinetic characterization of estradiol glucuronidation by liver microsomes and expressed UGT enzymes: The effects of organic solvents. European Journal of Drug Metabolism and Pharmacokinetics. 2024.49(3):343-353.
4.Chunhong Wu#, Yifei Xiao#, Caimei Wu#, Dihao Xie, Meixue Luo, Dingyi Yao, Min Chen*, Danyi Lu*. Regulation of BCRP expression and sulfasalazine pharmacokinetics by the nuclear receptor REV-ERB¦Á. Xenobiotica. 2023. 53(3):215-222.
5.Luyao Ma#, Meiping Huang#, Guanghui Sun, Yanke Lin, Danyi Lu*, Baojian Wu*. Puerariae lobatae radix protects against UVB-induced skin aging via antagonism of REV-ERB¦Á in mice. Frontiers in Pharmacology. 2022.13:1088294.
6.Danyi Lu, Zhigang Wang*, Baojian Wu*. Pharmacokinetics-based Chronotherapy. Current Drug Metabolism. 2022. 23(1):2-7.
7.Yi Wang#, Zhigang Wang#, Zhengping Wu, Menglin Chen, Dong Dong, Pei Yu, Danyi Lu*, Baojian Wu*. Involvement of REV-ERB¦Á dysregulation and ferroptosis in aristolochic acid I-induced renal injury. Biochemical Pharmacology. 2021.193: 114807.
8.Meiqing Li#, Danyi Lu#, Yulian Cheng#, Chunlei Wu, Jianchao Zhang, Wenli Shi, Zhihao Ding, Yanyan Li, Binghua Cheng, Xian Lin, Ximing Shao, Hongchang Li, Lijing Fang*, Ke Liu*, Wu Su*. A novel pyrrole-imidazole polyamide targets Aurora kinase A and suppresses tumor growth in vivo. Biochemical and Biophysical Research Communications. 2021.571:167-173.
9.Wenli Shi#, Danyi Lu#, Chunlei Wu, Meiqing Li, Zhihao Ding, Yanyan Li, Binghua Chen, Xian Lin, Wu Su, Ximing Shao, Zhihui Xia, Lijing Fang*, Ke Liu*, Hongchang Li*. Coibamide A kills cancer cells through inhibiting autophagy. Biochemical and Biophysical Research Communications. 2021.547:52-58.
10.Huan Zhao, Yongbin Tong, Danyi Lu*, Baojian Wu*. Circadian clock regulates hepatotoxicity of Tripterygium wilfordii through modulation of metabolism. Journal of Pharmacy and Pharmacology. 2020.72(12):1854-1864.
11.Danyi Lu#, Mengjing Zhao#, Min Chen, Baojian Wu*. Circadian clock-controlled drug metabolism: Implications for chronotherapeutics. Drug Metabolism and Disposition. 2020.48(5):395-406. (·âÃæÂÛÎÄ)
12.Danyi Lu#, Dong Dong#, Qian Xie, Zhijie Li, Baojian Wu*. Disposition of mianserin and cyclizine in UGT2B10-overexpressing human embryonic kidney 293 cells: identification of UGT2B10 as a novel N-glucosidation enzyme and breast cancer resistance protein as an N-glucoside transporter. Drug Metabolism and Disposition. 2018.46(7):970-979.
13.Danyi Lu, Dong Dong*, Baojian Wu*. Highly selective N-glucuronidation of four piperazine-containing drugs by UDP-glucuronosyltransferase 2B10. Expert Opinion on Drug Metabolism & Toxicology. 2018.14(9):989-998.
14.Danyi Lu, Shuai Wang, Qian Xie, Lianxia Guo, Baojian Wu*. Transcriptional regulation of human UDP-Glucuronosyltransferase 2B10 by farnesoid X receptor in human hepatoma HepG2 cells. Molecular Pharmaceutics. 2017.14(9):2899-2907.
15.Danyi Lu#, Qian Xie#, Baojian Wu*. N-glucuronidation catalyzed by UGT1A4 and UGT2B10 in human liver microsomes: Assay optimization and substrate identification. Journal of Pharmaceutical and Biomedical Analysis. 2017.145:692-703.
16.Danyi Lu#, Hui Liu#, Wencai Ye, Ying Wang, Baojian Wu*. Structure- and isoform-specific glucuronidation of six curcumin analogs. Xenobiotica. 2017.47(4):304-313.
17.Dong Dong#, Tianpeng Zhang#, Danyi Lu#, Jie Liu, Baojian Wu*. In vitro characterization of belinostat glucuronidation: demonstration of both UGT1A1 and UGT2B7 as the main contributing isozymes. Xenobiotica. 2017.47(4):277-283.
18.Danyi Lu#, Zhiguo Ma#, Tianpeng Zhang, Xingwang Zhang, Baojian Wu*. Metabolism of the anthelmintic drug niclosamide by cytochrome P450 enzymes and UDP-glucuronosyltransferases: metabolite elucidation and main contributions from CYP1A2 and UGT1A1. Xenobiotica. 2016.46(1):1-13.
19.Danyi Lu#, Dong Dong#, Zhong Liu, Yifei Wang*, Baojian Wu*. Metabolism elucidation of BJ-B11 (a heat shock protein 90 inhibitor) by human liver microsomes: identification of main contributing enzymes. Expert Opinion on Drug Metabolism & Toxicology. 2015.11(7):1029-40.
20.Danyi Lu, Jiayu Zhang, Zhenya Yang, Hongming Liu, Sha Li, Baojian Wu*, Zhiguo Ma*. Quantitative analysis of Cistanches Herba using high-performance liquid chromatography coupled with diode array detection and high-resolution mass spectrometry combined with chemometric methods. Journal of Separation Science, 2013, 36(12): 1945-1952.
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